Road, Kolkata - , West Bengal, India. E-mail: moc. Abstract Context: Mild cognitive impairment MCI is an under-diagnosed health problem in the community. Cognitive screening tools are widely used for MCI detection, but many of them lack sensitivity and specificity in MCI detection. On the basis of literature review, Short test of mental status STMS was selected for the present purpose.
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The Short Test of Mental Status STMS was specifically developed for use in dementia assessment and was intended to be more sensitive to problems of learning and mental agility that may be seen in mild cognitive impairment MCI. It covers a broad range of cognitive functions and uses a 4-word learning list with a delayed recall of approximately 3 minutes.
Volunteers with and without cognitive complaints or disorders were recruited. Each patient was evaluated by either a behavioral neurologist or a behavioral neurology fellow, who obtained a medical history from the patient and corroborating sources and performed a complete neurological examination including the STMS.
If cognitively impaired, the patient had a laboratory assessment and structural neuroimaging of the brain using either computed tomography or magnetic resonance imaging. Each patient underwent a 4-hour neuropsychological test, which included the MMSE 2 and a battery of standard neuropsychological tests.
The team consisted of nurses, a geriatrician E. Subjects were given a consensus evaluation based on all of the current information listed earlier and were evaluated as having normal cognition, MCI, or dementia according to the Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition.
Because the comparison of the MMSE and STMS was not prospectively conceived, the original study design did not maintain strict independence between test scores and clinical diagnoses. We grouped subjects according to their status at follow-up. Subjects were considered to have stable normal cognition if they remained cognitively healthy during the course of follow-up and for a minimum of 2 subsequent annual evaluations.
By this strategy, the diagnostic groupings were based on future status; although we used the same instruments and procedures as at baseline, subjects were grouped according to clinical course. As an additional approach to avoid circularity, we performed analyses in which we grouped subjects according to their CDR score.
We used t tests for bivariate comparisons. Areas under the receiver operating characteristic curves were compared using a modified Mann-Whitney U test statistic. Results The demographic features of the subjects grouped by categories are presented in Table 2.
There were more women than men in all groups. Subjects with stable normal cognition were slightly younger than the other subjects. The area under the receiver operating characteristic curve was modestly but significantly better for the STMS compared with the MMSE for discriminating between diagnostic groups stable normal cognition vs prevalent MCI. Table 3.
Short test of mental status in the detection of mild cognitive impairment in India
Clinical judgment and neuropsychological testing are integral in diagnosing MCI. For discriminating between prevalent MCI and AD, there was no difference in the performance of rest 2 tests. Tangalos, MD ; Bradley F. Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account.
A short test of mental status: description and preliminary results.