Sergei N Proshin In the last 30 years the use of X-ray contrast media RCM has increased significantly during urography, angiography, computed tomography, and operating procedures. Every year the world uses about 60 million doses of PKM, but, despite the use of newer and less nephrotoxic drugs, the risk of contrast-induced nephropathy CIN is still significant, especially among patients with prior renal impairment. Contrast induced nephropathy is a major cause of acute renal injury and is a huge problema in clinical practice. So far, con-tradictions remain in the understanding of many aspects of CIN. Contrast-induced nephropathy is acute renal failure ARF occurs within hours after intravenous administration of contrast sub-stances. Toxicity PKC determined their molecular structure and its ability to dissociate in aqueous solution into ions which consist of salts which dissociate into cations and anions.

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Thomsen and J. Webb, eds. Comprehensive information is presented on potential adverse reactions from the use of iodine-based contrast media, MRI contrast agents, ultrasound contrast agents, and barium. The book is aimed at radiologists, radiology residents, and fellows.

Other nonradiologists and their trainees, such as neurologists, neurosurgeons, orthopedists, cardiologists, and radiation therapists who have imaging facilities and use contrast media, can also benefit from the information, as can allied health professionals working with radiologists and nonradiologists. The book is organized into several sections 30 chapters that present comprehensive information on general issues regarding contrast media and their adverse reactions.

Also, specific clinical situations and the use of contrast media are described. Section 1 is 6 chapters covering general issues, including classification and terminology, requests for contrast-enhanced imaging, the legal aspects of off-label use of medicines, pharmacovigilance, the approval process for new contrast agents, and adverse events after contrast agent use. Section 2 addresses iodinated and gadolinium contrast agents and is divided into 3 subsections.

The first subsection, on general adverse reactions, contains 2 chapters on the prevention and management of acute adverse reactions. The second subsection, on renal adverse effects, has 3 chapters describing contrast medium—induced nephropathy and the use of contrast media on dialysis patients and non—insulin-dependent diabetic patients.

Four chapters on other adverse reactions comprise the last subsection. These chapters deal with pregnancy and lactation, pheochromocytoma, interactions with other drugs, and extravasation injury.

Section 3 covers iodinated contrast media and has 4 chapters describing late adverse reactions and the effects of contrast media on blood, endothelium, the lungs, and thyroid function.

Section 4, on MRI contrast media, has 3 subsections. The first subsection 3 chapters deals with non—tissue-specific extracellular media and describe chelates and stability, diagnostic efficacy, and radiography with gadolinium contrast agents. The second subsection 2 chapters presents gadolinium-based contrast agents and discusses acute and delayed adverse reactions, including nephrogenic systemic sclerosis.

The last subsection 2 chapters describes gadolinium-based and non—gadolinium-based contrast agents. Section 5 presents the safety of ultrasound contrast media, and Section 6 deals with safety issues concerning the use of barium preparations.

This is an excellent book that I highly recommend. It belongs in the libraries of radiologists and training programs. This comprehensive review is written in such a way that the flow of information is preserved throughout the book.

The multiple authors and editors are to be commended for such dedication and detail. Day-to-day imaging and management scenarios encountered by radiologists are easily found in this resource book. The reader is advised to compare the American College of Radiology guidelines on contrast media, which can be found online, with those in this book, given the differences in the availability and use of contrast media between Europe and the United States.


ESUR Guidelines on Contrast Media - European Society of Urogenital Radiology

Thomsen and J. Webb, eds. Comprehensive information is presented on potential adverse reactions from the use of iodine-based contrast media, MRI contrast agents, ultrasound contrast agents, and barium. The book is aimed at radiologists, radiology residents, and fellows.


ESUR Guidelines on Contrast Media

There is no clinical evidence of the guidelijes of premedication. Large volume of contrast medium. We hope that you find our guidelines very helpful in your daily practice. Scrotal imaging When there is a very strong indication for guidelones MR, the smallest possible dose of one of the most stable gadolinium contrast agents see Contrast agents: The patient should discuss with the doctor whether the breast milk should be discarded in the 24 hours after contrast medium. A suitable protocol is intravenous normal saline, 1. Supportive treatment Severe, protracted: In all patients use the smallest amount of contrast medium necessary for a diagnostic result.


Contrast Media: Safety Issues and ESUR Guidelines

Peter Aspelin S. Thomsen,1 S. Disagreement within the com- mittee is usually rational and without commercial Since the Contrast Media Safety Committee of the influence. The work of the committee involves choosing European Society of Urogenital Radiology has released topics of clinical importance regarding the safe use of 15 guidelines regarding safety in relation to the use of contrast media and allocating one or two appropriate radiographic, ultrasonographic, and magnetic resonance members of the committee to produce the first draft of contrast media.

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